This bison lasagna is a hearty twist on a classic dish, using lean bison meat for a rich flavor. It layers up perfectly with pasta, cheese, and tomato sauce!
If you think regular lasagna is good, wait until you try this! I love how the bison adds a special kick, making it a family favorite every time. 🍽️
Key Ingredients & Substitutions
Ground Bison: This lean meat gives the lasagna a unique flavor. If you can’t find bison, ground turkey or beef can be good alternatives, but keep in mind they will change the dish’s taste and richness.
Ricotta Cheese: Ricotta adds a creamy texture. If you’re looking for a lighter option, cottage cheese works well too. You can also use vegan ricotta made from blended tofu and nutritional yeast.
Lasagna Noodles: Regular lasagna noodles are perfect, but you can use whole wheat or gluten-free noodles. No-boil noodles are also an option if you’re short on time.
Cheeses: Mozzarella and Parmesan are classics, but feel free to experiment! Cheddar or a blend of Italian cheeses could add a new twist to your lasagna.
What’s the Best Way to Layer Lasagna?
Layering lasagna is an art! It’s important to create a balanced structure so each bite has a mix of flavors. Start with sauce on the bottom to prevent sticking. Here’s my tip:
- Begin with a thin layer of sauce on the bottom of your baking dish.
- Place the cooked noodles in a single layer, ensuring they slightly overlap.
- Spread about a third of the ricotta mixture, then add a layer of meat sauce, followed by a sprinkle of mozzarella.
- Repeat these layers two more times, finishing with noodles, sauce, and a sprinkle of cheese on top.
- Don’t forget to let it rest before cutting; this helps everything hold together!
By taking your time with the layers, you’ll create a delicious lasagna that impresses everyone at the table! Enjoy the cooking process!

How to Make Bison Lasagna
Ingredients You’ll Need:
For the Meat Sauce:
- 1 pound ground bison
- 1 tablespoon olive oil
- 1 large onion, finely chopped
- 3 cloves garlic, minced
- 1 (28-ounce) can crushed tomatoes
- 1 (15-ounce) can tomato sauce
- 2 tablespoons tomato paste
- 1 teaspoon dried basil
- 1 teaspoon dried oregano
- ½ teaspoon crushed red pepper flakes (optional)
- Salt and pepper to taste
For the Cheese Mixture:
- 3 cups ricotta cheese
- 2 cups shredded mozzarella cheese
- 1 cup grated Parmesan cheese
- 1 large egg
Other Ingredients:
- 12 lasagna noodles, cooked and drained
- Fresh parsley or basil, chopped (for garnish)
How Much Time Will You Need?
This delightful dish takes about 30 minutes to get everything ready and then about 45 minutes to bake. After baking, it’s best to let it sit for about 10-15 minutes before serving. In total, you’re looking at around 1 hour and 15 minutes!
Step-by-Step Instructions:
1. Preheat the Oven:
Start by preheating your oven to 375°F (190°C). This way, it’s nice and hot when your lasagna is ready to go in!
2. Make the Meat Sauce:
In a large skillet, heat the olive oil over medium heat. Add the chopped onion and sauté for about 5 minutes, or until it becomes soft and translucent. Add the minced garlic and cook for an additional minute until it’s fragrant!
Next, add the ground bison and stir it around until it’s browned and cooked through, about 7-10 minutes. If there’s excess fat, drain it out. Now, stir in the crushed tomatoes, tomato sauce, and tomato paste. Add the dried basil, oregano, red pepper flakes, salt, and pepper to taste. Simmer this mixture for 15-20 minutes, stirring occasionally.
3. Prepare the Cheese Mixture:
In a mixing bowl, combine the ricotta cheese, egg, half of the grated Parmesan cheese, salt, and pepper. Mix it well until everything is nicely blended.
4. Layer the Lasagna:
Spread a thin layer of the meat sauce on the bottom of a 9×13 inch baking dish. Place four lasagna noodles on top, slightly overlapping them.
Now, spread one-third of the ricotta mixture over the noodles, followed by one-third of the meat sauce. Sprinkle a layer of mozzarella cheese on top.
Repeat the layering process two more times until all ingredients are used up. Finish with a final layer of meat sauce and the remaining mozzarella and Parmesan cheese on top.
5. Bake:
Cover the baking dish with foil and place it in the preheated oven. Bake for 25 minutes, then remove the foil and bake for an additional 20 minutes, or until the cheese is bubbly and golden brown.
6. Serve:
Once done, remove the lasagna from the oven and let it rest for 10-15 minutes. This helps it set so you can cut nice pieces. Garnish with chopped fresh parsley or basil before serving!
Enjoy every cheesy bite of your flavorful and rich Bison Lasagna!
Can I Use Ground Beef Instead of Bison?
Absolutely! Ground beef is a great substitute if bison isn’t available. Just be aware that beef is generally higher in fat, which may alter the richness of the sauce slightly.
Can I Prepare This Dish in Advance?
Yes, you can assemble the lasagna ahead of time and store it in the refrigerator for up to 24 hours before baking. Just add a few extra minutes to the baking time if it’s cold from the fridge.
How to Store Leftovers?
Leftover lasagna can be stored in an airtight container in the fridge for up to 3-4 days. You can reheat it in the microwave or bake it in the oven at 350°F (175°C) until warmed through.
What Can I Serve with Bison Lasagna?
Bison lasagna pairs beautifully with a fresh green salad or garlic bread. You might also enjoy it with a side of steamed vegetables for a complete meal!



